The largest city in Kansas is Wichita, with a population of 389,255 people as of 2019. It is the principal city of the Wichita metropolitan area which had an estimated population of 644,888 in 2018. Wichita is located near the Arkansas River and along Interstate 35 in south-central Kansas. It is known for its rich history and cultural heritage as well as its vibrant downtown area and entertainment district. The city has become an important regional center for industry, healthcare, education, retail, transportation and technology. With a diverse economy and plenty of attractions, Wichita is a great place to live and work.